classmate response #3

respond to class mate #1

Nurses play a very crucial role in helping psychiatric patients who refuse to take their medication. Nurses know about dealing with these patients, and they try their best to ensure that the patient has accepted the medication. (Blough & Loprinzi, 2019). Some of these patients are so stubborn that they say that the medicine given to them is poison. Nurses use their logics and ethical grounds in ensuring the patients have taken the medication since the refusal to take medicine contributes to low-quality life and increases the relapse rate. Therefore, nurses need to analyze how using nursing’s logical and ethical grounds to make sure the patients with paranoid delusions accept taking his or her antipsychotic drugs.

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As a nurse, when a patient refuses to take medication, you should enlighten the patient on the possible dangers associated with medicine refusal. You should advise the patient about the importance of their life and tell them that the refusal to take the medication lowers the quality of his or her life. In turn, nurses should go on to explain to the patient that the non-acceptance of treatment would endanger themselves and others (Abram & Forbes, 2019). The nurse should express emotions when explaining these dangers and not just words. Doing this helps the patient realize the possible dangers of not taking the prescribed medicine not just through verbal reasoning but through emotional identification.

In cases of medicine refusal by a patient, a nurse should engage the patient’s family members and friends to ensure the patient adheres to follow-ups on the appointments and medication compliance. The nurse can ensure that the family members and friends help the patient by explaining and reminding the consequences of lack of medication compliance and need to maintain follow-up appointments (Blough & Loprinzi, 2019).

respond class mate #2

Scenario 1: (Antipsychotic Drugs ) Most psychotropic drug interactions occur as a result of the effects on the CYP-450 system. If an inhibitor of the CYP-450 3A4 enzyme were given (e.g. grapefruit juice) with psychotropic drugs metabolized by this enzyme (e.g. sertraline, bupropion, diazepam, haloperidol), what would be the effect? (Typically an entire grapefruit or 8 ounces of juice would be enough to trigger pharmacokinectic changes (Boyd & Luebbert, 2020; Keltner & Steele, 2019) ?


Grapefruit juice contains furanocoumarins that stop CYP-450 3A4 from being absorbed in the GI. As a result of the inhibitory effect of the enzyme, more of the drug is absorbed, making it more powerful (Should you avoid grapefruit juice, 2014).). If an inhibitor of the CYP-450 3A4 such as grapefruit juice was given with medications such as sertraline, bupropion, diazepam, haloperidol the result would be higher serum levels and a higher effect from drugs. The nurse would notice an exaggerated effect of the medication. For example, benzodiazepines can extend the life of many benzodiazepines that would increase the sedative effect of the medication such as diazepam. Watson (2012) Caritas “engaging in transpersonal teaching and learning within context of caring relationship” is the one that I would use to help provide the patient with education regarding the side effect, and drug- food interaction, and dru-drug interaction.

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